Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15639425 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EATMLMNARAB9A | |
| SCHEMBL2379504 | 0.74 | MAPK1 (0.56) | SMN1; SMN2KDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL30662375 | 0.74 | MAPK1 (0.56) | SMN1; SMN2KDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL6807071 | 0.74 | MEN1 (0.51) | SMN1; SMN2KDM4EATMLMNARAB9A | |
| SCHEMBL179064 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EATMLMNARAB9A | |
| SCHEMBL12260592 | 0.73 | ALDH1A1 (0.65) | SMN1; SMN2KDM4EATMLMNARAB9A | |
| SCHEMBL16449993 | 0.73 | ACSS2 (0.56) | SMN1; SMN2KDM4ELMNARAB9AALDH1A1 | |
| SCHEMBL1171430 | 0.73 | MEN1 (0.69) | SMN1; SMN2KDM4EATMLMNARAB9A | |
| SCHEMBL353890 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EATMLMNARAB9A | |
| SCHEMBL1053419 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4EATMLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |