Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245913 | 0.84 | RAB9A (0.51) | SMN1; SMN2MAPTMETAP2RAB9ANPC1 | |
| SCHEMBL15090444 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTNOTUMRAB9ANPC1 | |
| SCHEMBL1645103 | 0.78 | METAP2 (0.50) | MAPTNOTUMMETAP2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10565482 | 0.76 | METAP2 (0.48) | MAPTNOTUMMETAP2RAB9ANPC1 | |
| SCHEMBL28822256 | 0.74 | LTA4H (0.51) | MAPTNOTUMMETAP2ALDH1A1KDM4E | |
| Methylamine SCHEMBL27885520 | 0.73 | METAP2 (0.46) | MAPTNOTUMMETAP2RAB9ANPC1 | |
| SCHEMBL10625604 | 0.69 | ABL1 (0.45) | SMN1; SMN2MAPTRAB9ANPC1NFKB1 | |
| SCHEMBL16766999 | 0.68 | LMNA (0.36) | SMN1; SMN2MAPTNOTUMMETAP2RAB9A | |
| SCHEMBL2053083 | 0.68 | CYP2A6 (0.40) | SMN1; SMN2MAPTRAB9ANPC1PPARG | |
| SCHEMBL2095935 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTNOTUMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | SMN1; SMN2 3198/4885MAPT 4875/4885NOTUM 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.