Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 2/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244461 | 0.84 | TYR (0.57) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL7039051 | 0.84 | SHBG (0.43) | AMY1AESR1ESR2HIF1ACYP2C9 | |
| SCHEMBL8470006 | 0.84 | TYR (0.57) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL26375867 | 0.84 | AMY1A (0.56) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL30375444 | 0.83 | TYR (0.42) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL3196356 | 0.83 | TYR (0.42) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL29636469 | 0.83 | TYR (0.42) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL14217893 | 0.82 | TYR (0.35) | TYRAMY1AHIF1ACYP2C9CYP2C19 | |
| SCHEMBL10446211 | 0.81 | AMY1A (0.52) | TYRAMY1AESR1ESR2HIF1A | |
| SCHEMBL8066841 | 0.81 | AMY1A (0.67) | TYRAMY1AESR1ESR2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150044117-A1 | CAVITAND COMPOSITIONS AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150044117-A1 | CAVITAND COMPOSITIONS AND METHODS OF USE THEREOF | VCL, TMEM109, GYS1 | TYR 4559/4885AMY1A 1319/4885ESR1 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.