SCHEMBL31244461

SCHEMBL31244461

Cc1c(O)ccc(Cc2ccc(O)c(C)c2O)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 1/20 0.57
▸ AMY1A P0DUB6 1/20 0.47
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ MAPT P10636 2/20 0.41
▸ HSPA5 P11021 2/20 0.39
▸ SHBG P04278 1/20 0.39
▸ HIF1A Q16665 2/20 0.38
▸ ALOX15 P16050 2/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ ESR2 Q92731 1/20 0.38
▸ SLC22A1 O15245 1/20 0.38
▸ USP2 O75604 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ HSP90AA1 P07900 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ HSPD1 P10809 1/20 0.38
▸ IDO1 P14902 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8470006 1.00 TYR (0.57) TYRAMY1AMEN1KMT2AMAPT
SCHEMBL10446211 0.88 AMY1A (0.52) TYRAMY1AMEN1KMT2AMAPT
SCHEMBL8066841 0.88 AMY1A (0.67) TYRAMY1AMEN1KMT2AMAPT
SCHEMBL16451675 0.84 TYR (0.45) TYRAMY1AMEN1KMT2AMAPT
SCHEMBL10011371 0.83 BCL2 (0.53) TYRMEN1KMT2AHIF1AALOX15
SCHEMBL9644973 0.83 TYR (0.47) TYRAMY1AMEN1KMT2AMAPT
SCHEMBL18744075 0.83 KEAP1 (0.50) TYRMEN1KMT2AMAPTESR1
SCHEMBL28845277 0.83 TYR (0.55) TYRAMY1AMEN1KMT2AMAPT
SCHEMBL70108 0.83 TYR (0.60) TYRMEN1KMT2AMAPTSHBG
SCHEMBL4063406 0.82 TYR (0.44) TYRAMY1AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565930-B2 Seal member and production method thereof CANON KABUSHIKI KAISHA (JP) 2026-03-03 — — US disclosed
US-20240337317-A1 SEAL MEMBER AND PRODUCTION METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2024-10-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565930-B2 Seal member and production method thereof RIPK1, SLK, STK39 TYR 4202/4885AMY1A 3509/4885MEN1 4536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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