Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454832 | 0.71 | RAB9A (0.52) | KDM4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL16454903 | 0.71 | ALOX15 (0.47) | HPGDHSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL16454902 | 0.70 | MAPK1 (0.47) | HPGDHSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL16454822 | 0.69 | HSD11B1 (0.43) | HPGDALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL16454805 | 0.69 | MAPT (0.50) | HSD17B10ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL16454833 | 0.69 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16454806 | 0.69 | KMT2A (0.49) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16454807 | 0.69 | HSD11B1 (0.38) | MAPTRAB9AMEN1KMT2ACYP1A2 | |
| SCHEMBL16454821 | 0.69 | HSD11B1 (0.44) | HPGD | |
| SCHEMBL16454906 | 0.69 | GAA (0.45) | HPGDHSD17B10ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |