SCHEMBL1645522

SCHEMBL1645522

Clc1cc(Cl)c(Cl)c(CCSSCCc2c(Cl)c(Cl)cc(Cl)c2Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.43
HSD17B10 Q99714 4/20 0.43
TSHR P16473 4/20 0.43
CYP3A4 P08684 3/20 0.43
MAPK1 P28482 2/20 0.43
HIF1A Q16665 2/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
USP2 O75604 1/20 0.43
EGFR P00533 1/20 0.43
LMNA P02545 1/20 0.43
ESR1 P03372 1/20 0.43
ERBB2 P04626 1/20 0.43
CYP1A2 P05177 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
PGR P06401 1/20 0.43
POLB P06746 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HTR1A P08908 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1645142 0.78
SCHEMBL1648004 0.75 ALDH1A1 (0.39) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL27545982 0.72 HPGD (0.44) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL11240352 0.67 HPGD (0.50) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL14143885 0.65 HPGD (0.48) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL6441243 0.65 HPGD (0.54) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL13577661 0.65 HSD17B10 (0.74) HPGDHSD17B10TSHRCYP3A4MAPK1
SCHEMBL1646153 0.62 TSHR (0.42) TSHRCYP3A4
Pentachlorobenzene SCHEMBL11455164 0.61 CYP3A4 (1.00) HPGDHSD17B10TSHRCYP3A4MAPK1
Pentachlorobenzene SCHEMBL183144 0.61 CYP3A4 (1.00) HPGDHSD17B10TSHRCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed