SCHEMBL1648004

SCHEMBL1648004

Clc1cc(Cl)c(CCSSCCc2c(Cl)cc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TSHR P16473 5/20 0.36
CYP3A4 P08684 4/20 0.36
HSD17B10 Q99714 4/20 0.36
RECQL P46063 3/20 0.36
MAPK1 P28482 3/20 0.33
HPGD P15428 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
ALOX15 P16050 2/20 0.33
ALOX12 P18054 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1645522 0.75 HPGD (0.43) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL3415768 0.72 ALDH1A1 (0.43) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL18378725 0.72 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL11366462 0.72 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL10061037 0.72 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL1646153 0.72 TSHR (0.42) TSHRCYP3A4TP53TAAR1
SCHEMBL6130333 0.72 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL16404692 0.72 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL1648141 0.70 CYP1A2 (0.57) CYP3A4MAPK1CYP1A2CYP2C9HTT
SCHEMBL29074259 0.69 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4HSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed