Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16457850 | 0.88 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1SLC6A2 | |
| Hydrochloric Acid SCHEMBL16457853 | 0.87 | TACR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL16458693 | 0.80 | OPRL1 (0.34) | OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL16459482 | 0.69 | CALM1 (0.33) | CALM1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL16459103 | 0.69 | OPRM1 (0.33) | OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL10322364 | 0.68 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL16457743 | 0.67 | CALM1 (0.31) | CALM1 | |
| SCHEMBL12506450 | 0.66 | CALM1 (0.41) | CALM1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL16459906 | 0.66 | CALM1 (0.33) | CALM1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10318146 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012056-A1 | METHOD FOR PRODUCING 1-HEXENE | AP2A1, AP1M1, ME1 | SLC6A2 4749/4885SLC6A3 4766/4885CALM1 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.