Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16460750 | 0.77 | TP53 (0.37) | TSHRTP53CYP19A1ELANECALM1 | |
| SCHEMBL243501 | 0.77 | TSHR (0.39) | TSHRALDH1A1TP53AOC3NR1H2 | |
| SCHEMBL5388447 | 0.76 | TSHR (0.42) | TSHRALDH1A1TP53AOC3NR1H2 | |
| SCHEMBL109029 | 0.74 | TSHR (0.41) | TSHRALDH1A1TP53AOC3NR1H2 | |
| SCHEMBL1107767 | 0.73 | TP53 (0.48) | TSHRALDH1A1TP53NR1H2NR1H3 | |
| SCHEMBL13550868 | 0.72 | TSHR (0.39) | TSHRALDH1A1TP53AOC3NR1H2 | |
| SCHEMBL14665751 | 0.72 | TSHR (0.39) | TSHRALDH1A1TP53AOC3NR1H2 | |
| SCHEMBL14689277 | 0.72 | TP53 (0.34) | TSHRTP53NR1H2NR1H3CYP19A1 | |
| SCHEMBL1271761 | 0.72 | TP53 (0.42) | TSHRALDH1A1TP53NR1H2NR1H3 | |
| SCHEMBL109170 | 0.71 | TP53 (0.42) | TSHRALDH1A1TP53AOC3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303059-B2 | Chemoselective enrichment for compound isolation | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-20140107328-A1 | CHEMOSELECTIVE ENRICHMENT FOR COMPOUND ISOLATION | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107328-A1 | CHEMOSELECTIVE ENRICHMENT FOR COMPOUND ISOLATION | PAH, HAAO, APEH | TSHR 4644/4885ALDH1A1 417/4885TP53 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.