Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388447 | 0.81 | TSHR (0.42) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL109029 | 0.79 | TSHR (0.41) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL1107767 | 0.78 | TP53 (0.48) | TSHRALDH1A1TP53TAAR1CALM1 | |
| SCHEMBL13550868 | 0.77 | TSHR (0.39) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL14665751 | 0.77 | TSHR (0.39) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL16459782 | 0.77 | TSHR (0.35) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL109170 | 0.76 | TP53 (0.42) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL534142 | 0.74 | TSHR (0.41) | TSHRALDH1A1TP53AOC3TAAR1 | |
| SCHEMBL19926794 | 0.74 | KCNH2 (0.46) | ALDH1A1TP53AOC3TAAR1IDO1 | |
| SCHEMBL15949869 | 0.74 | TSHR (0.37) | TSHRALDH1A1TP53AOC3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307808-A1 | Siloxane Traction Fluids with Ring-Shaped Branch Structures and Method of Using | DOW SILICONES CORPORATION | 2015-10-29 | — | — | US | claimed |
| EP-2925841-A1 | SILOXANE TRACTION FLUIDS WITH RING-SHAPED BRANCH STRUCTURES AND METHOD OF USING | Dow Corning Corporation (US) | 2015-10-07 | — | — | EP | claimed |
| WO-2014085522-A1 | SILOXANE TRACTION FLUIDS WITH RING-SHAPED BRANCH STRUCTURES AND METHOD OF USING | DOW CORNING CORPORATION (US) | 2014-06-05 | — | — | WO | claimed |
| US-8642520-B2 | Silicone based lubricant compositions | VANDERBILT CHEMICALS, LLC (US) | 2014-02-04 | — | — | US | claimed |
| US-20120004151-A1 | SILICONE BASED LUBRICANT COMPOSITIONS | R.T. VANDERBILT COMPANY, INC. (US) | 2012-01-05 | — | — | US | claimed |
| US-5599474-A | SILICON OIL CARRIER FLUID, MAGNETORHEOLOGICAL PARTICLES | LORD CORPORATION (US) | 1997-02-04 | — | — | US | claimed |
| EP-0672293-A4 | LOW VISCOSITY MAGNETORHEOLOGICAL MATERIALS. | LORD CORP (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0672293-A1 | LOW VISCOSITY MAGNETORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1994010692-A1 | LOW VISCOSITY MAGNETORHEOLOGICAL MATERIALS | LORD CORPORATION (US) | 1994-05-11 | — | — | WO | claimed |
| US-4170957-A | Fixing device using polyarylsiloxanes as release agents | XEROX CORPORATION (US) | 1979-10-16 | — | — | US | claimed |
| US-4065586-A | FUSING ELECTROSCOPIC TONER IMAGES TO A SUBSTRATE, SOFTENING | XEROX CORPORATION (US) | 1977-12-27 | — | — | US | claimed |
| CN-114466904-A | Heat-conductive silicone composition and method for producing same | 富士高分子工业株式会社 | 2022-05-10 | — | — | CN | disclosed |
| CN-114466905-A | Heat-conductive silicone composition and method for producing same | 富士高分子工业株式会社 | 2022-05-10 | — | — | CN | disclosed |
| CN-109641482-A | The preparation of the cis- -1,4- polydiene of multiple silane functionals with the Si―H addition reaction in situ preparation by polymer glue | 株式会社普利司通 | 2019-04-16 | — | — | CN | disclosed |
| EP-3221408-A1 | CURABLE, HIGHLY TRANSPARENT SILICONE COMPOSITION WITH IMPROVED MECHANICS, FOR OPTICAL COMPONENTS | Wacker Chemie AG (DE) | 2017-09-27 | — | — | EP | disclosed |
| US-4170957-A | Fixing device using polyarylsiloxanes as release agents | XEROX CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4065586-A | FUSING ELECTROSCOPIC TONER IMAGES TO A SUBSTRATE, SOFTENING | XEROX CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065586-A | FUSING ELECTROSCOPIC TONER IMAGES TO A SUBSTRATE, SOFTENING | XEROX CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4043924-A | Water based green tire lubricant | GENERAL ELECTRIC COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4039143-A | Organic hydrocarbon solvent-based green tire lubricant and process | GENERAL ELECTRIC COMPANY (US) | 1977-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004151-A1 | SILICONE BASED LUBRICANT COMPOSITIONS | SRM, SMS, PIEZO1 | TSHR 3728/4885ALDH1A1 2593/4885TP53 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.