Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CALCA | P06881 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154317 | 0.85 | PRCP (0.46) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL1101370 | 0.85 | PRCP (0.46) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL14833617 | 0.84 | ALDH1A1 (0.43) | HPGDKMT2AALDH1A1 | |
| SCHEMBL14833501 | 0.83 | MAOA (0.43) | HTR2CHTR2AHTR2BSIGMAR1ALDH1A1 | |
| SCHEMBL14833444 | 0.81 | HTR2C (0.45) | HTR2CHTR2AHTR2B | |
| SCHEMBL6301700 | 0.80 | SIGMAR1 (0.42) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL3978422 | 0.80 | SLC6A2 (0.41) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL410563 | 0.80 | P2RX7 (0.43) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL27843488 | 0.80 | SLC6A2 (0.41) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| SCHEMBL470870 | 0.80 | P2RX7 (0.43) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906544-A1 | SUBSTITUTED PHENYLCARBAMATE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014056958-A1 | SUBSTITUTED PHENYLCARBAMATE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-17 | — | — | WO | disclosed |