SCHEMBL16467684

SCHEMBL16467684

[CH2]OS(=O)(=O)c1ccc(Br)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 3/20 0.43
▸ MAPK10 P53779 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ FABP4 P15090 2/20 0.41
▸ FABP5 Q01469 1/20 0.40
▸ LDHA P00338 1/20 0.39
▸ IKBKB O14920 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ CA1 P00915 3/20 0.35
▸ CA2 P00918 3/20 0.35
▸ CA4 P22748 2/20 0.35
▸ CA6 P23280 2/20 0.35
▸ LMNA P02545 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ PLCG1 P19174 1/20 0.33
▸ CA9 Q16790 2/20 0.32
▸ CDK2 P24941 1/20 0.32
▸ CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22550972 0.89 CA2 (0.39) RXFP1MAPK10NPSR1MEN1KMT2A
SCHEMBL16467685 0.81 RXFP1 (0.47) RXFP1MAPK10NPSR1MEN1KMT2A
SCHEMBL15352841 0.78 CYP1A2 (0.48) RXFP1NPSR1MEN1KMT2AFABP4
SCHEMBL15352744 0.78 ALDH1A1 (0.49) NPSR1FABP4FABP5LDHASLC40A1
SCHEMBL16467622 0.76 POLB (0.44) RXFP1CA1CA2LMNACA9
SCHEMBL16467867 0.76 CA1 (0.56) MEN1KMT2ACA1CA2CA4
SCHEMBL15514563 0.76 LDHA (0.64) RXFP1MAPK10NPSR1MEN1KMT2A
SCHEMBL3578778 0.75 FABP4 (0.51) RXFP1MAPK10NPSR1MEN1KMT2A
SCHEMBL15461558 0.75 RXFP1 (0.50) RXFP1MAPK10NPSR1MEN1KMT2A
SCHEMBL30987398 0.75 RXFP1 (0.46) RXFP1MAPK10NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 — — EP disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 — — US disclosed
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 — — US disclosed
CN-104245689-A Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL CO 2014-12-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES CBR3, CYCS, CBR1 RXFP1 862/4885MAPK10 1541/4885NPSR1 1339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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