Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19915073 | 0.95 | NPSR1 (0.61) | LMNANPSR1SMN1; SMN2DRD2HPGD | |
| SCHEMBL1645759 | 0.92 | DRD2 (0.52) | LMNANPSR1SMN1; SMN2DRD2RAB9A | |
| SCHEMBL1673520 | 0.84 | HTR2C (0.54) | LMNANPSR1SMN1; SMN2DRD2ALDH1A1 | |
| SCHEMBL2090904 | 0.84 | RAB9A (0.49) | LMNANPSR1SMN1; SMN2DRD2HPGD | |
| Hydrochloric Acid SCHEMBL15819292 | 0.83 | HTR2C (0.55) | LMNANPSR1SMN1; SMN2DRD2MAPT | |
| SCHEMBL6887466 | 0.81 | HTR3A (0.66) | LMNANPSR1SMN1; SMN2DRD2MAPT | |
| SCHEMBL6890751 | 0.81 | HTR3A (0.66) | LMNANPSR1SMN1; SMN2DRD2MAPT | |
| SCHEMBL6813677 | 0.81 | ALDH1A1 (0.58) | LMNASMN1; SMN2TSHRKDM4EGAA | |
| SCHEMBL7478390 | 0.80 | MAPT (0.43) | LMNANPSR1SMN1; SMN2DRD2RAB9A | |
| SCHEMBL20931339 | 0.78 | KDM4E (0.54) | LMNANPSR1SMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4665239-B2 | — | — | 2011-04-06 | — | — | JP | claimed |
| JP-2002512230-A | — | — | 2002-04-23 | — | — | JP | claimed |
| EP-1071668-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | Du Pont Pharmaceuticals Company (US) | 2001-01-31 | — | — | EP | claimed |
| WO-1999054308-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-10-28 | — | — | WO | claimed |
| EP-1071668-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | Du Pont Pharmaceuticals Company (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054308-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-10-28 | — | — | WO | disclosed |