SCHEMBL16468562

SCHEMBL16468562

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nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.47
DPP8 Q6V1X1 2/20 0.47
DPP9 Q86TI2 2/20 0.47
BACE1 P56817 10/20 0.42
CTSD P07339 2/20 0.42
BMP1 P13497 1/20 0.39
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
KMT2A Q03164 1/20 0.37
GNPAT O15228 1/20 0.37
BACE2 Q9Y5Z0 1/20 0.36
ENPEP Q07075 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28081126 0.85 DPP4 (0.58) DPP4DPP8DPP9BACE1CTSD
SCHEMBL7405823 0.85 DPP4 (0.43) DPP4DPP8DPP9BACE1CTSD
SCHEMBL2223562 0.83 MME (0.40) BACE1CTSDGNPATBACE2
SCHEMBL2196474 0.82 DPP4 (0.47) DPP4DPP8DPP9BACE1CTSD
SCHEMBL2184922 0.82 DPP4 (0.47) DPP4DPP8DPP9BACE1CTSD
SCHEMBL29478400 0.82 BACE1 (0.54) DPP4DPP8DPP9BACE1CTSD
SCHEMBL31514361 0.81 ALOX15 (0.50) DPP4DPP8DPP9BACE1CTSD
SCHEMBL2182137 0.80 OPRD1 (0.38) DPP4DPP8DPP9BACE1CTSD
SCHEMBL30656940 0.80 BMP1 (0.58) DPP4DPP8DPP9BACE1CTSD
SCHEMBL2182252 0.79 DPP4 (0.38) DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9173951-B2 Carbohydrate-based drug delivery polymers and conjugates thereof NEKTAR THERAPEUTICS (US) 2015-11-03 US disclosed
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF NEKTAR THERAPEUTICS (US) 2015-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051371-A1 CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF STT3B, STT3A, DDOST DPP4 193/4885DPP8 274/4885DPP9 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.