SCHEMBL16469872

SCHEMBL16469872

c1ccc(Sc2ccc(N3CSc4ccccc43)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.33
HTR3A P46098 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
HTR2C P28335 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
NPC1 O15118 2/20 0.32
SIGMAR1 Q99720 1/20 0.32
MEN1 O00255 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
NOTUM Q6P988 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11995114 0.84 SIGMAR1 (0.39) MAOAALDH1A1HPGDNPC1SIGMAR1
SCHEMBL16470234 0.78 NPC1 (0.39) MAOAALDH1A1HPGDNPC1RAB9A
SCHEMBL16470372 0.78 LMNA (0.40) HPGDMEN1KMT2A
SCHEMBL16470166 0.78 TSHR (0.43) ALDH1A1HPGDMEN1RAB9AKMT2A
SCHEMBL28957204 0.75 NOTUM (0.33) MAOAALDH1A1NPC1MEN1RAB9A
SCHEMBL16470117 0.74 BRD4 (0.39) MAOAMAOBALDH1A1NPC1MEN1
SCHEMBL16470622 0.72 HTR3A (0.40) HTR3AHTR2CALDH1A1HPGDSIGMAR1
SCHEMBL16470683 0.67 MEN1 (0.50) ALDH1A1MEN1KMT2ASMN1; SMN2NOTUM
SCHEMBL16470193 0.67 ALDH1A1 (0.50) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL16470648 0.66 HSD17B3 (0.43) MAOAMAOBNPC1SIGMAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829605-B2 Polarized film, optical film, and image display device NITTO DENKO CORPORATION (JP) 2017-11-28 US disclosed
US-20160152002-A1 TRANSPARENT CONDUCTIVE LAMINATED FILM, METHOD FOR MANUFACTURING SAME, AND TOUCH PANEL NITTO DENKO CORPORATION (JP) 2016-06-02 US disclosed
CN-105324240-A Transparent conductive laminated film, method for producing same, and touch panel NITTO DENKO CORP 2016-02-10 CN disclosed
US-20150152299-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-06-04 US disclosed
US-20150116817-A1 ACTIVE ENERGY RAY CURABLE ADHESIVE COMPOSITION, POLARIZING FILM AND METHOD FOR PRODUCING SAME, OPTICAL FILM AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-04-30 US disclosed
US-20150049380-A1 POLARIZED FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-02-19 US disclosed