Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316224 | 0.88 | TGFBR1 (0.41) | TGFBR1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16267884 | 0.81 | TGFBR1 (0.38) | TGFBR1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11866190 | 0.81 | TGFBR1 (0.38) | TGFBR1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16384922 | 0.81 | EPHX1 (0.39) | TGFBR1ALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL2612361 | 0.81 | KDM4E (0.50) | TGFBR1ALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL112305 | 0.79 | TGFBR1 (0.36) | TGFBR1ALDH1A1KDM4EMAPK1HIF1A | |
| SCHEMBL1160400 | 0.79 | — | — | |
| SCHEMBL511744 | 0.78 | TGFBR1 (0.33) | TGFBR1ALDH1A1 | |
| SCHEMBL2428291 | 0.78 | TGFBR1 (0.33) | TGFBR1ALDH1A1 | |
| SCHEMBL632876 | 0.78 | KDM4E (0.46) | TGFBR1ALDH1A1KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181375-B2 | Fluorescent potassium ion sensors | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizo (US) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | KCNN1, KCNN2, KCNN3 | TGFBR1 3152/4885ALDH1A1 3959/4885NPC1 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.