SCHEMBL511744

SCHEMBL511744

C=C(C)C(=O)NCCNC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.33
ALDH1A1 P00352 2/20 0.31
TP53BP1 Q12888 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1567367 0.88 TP53BP1 (0.41) TGFBR1TP53BP1
SCHEMBL316224 0.84 TGFBR1 (0.41) TGFBR1ALDH1A1
SCHEMBL22804705 0.81 TGFBR1 (0.34) TGFBR1ALDH1A1
SCHEMBL6683821 0.79 TDP1 (0.51) ALDH1A1
SCHEMBL23318197 0.79 ALOX15 (0.34)
SCHEMBL16480239 0.78 TGFBR1 (0.35) TGFBR1ALDH1A1
SCHEMBL16267884 0.78 TGFBR1 (0.38) TGFBR1ALDH1A1
SCHEMBL16384922 0.78 EPHX1 (0.39) TGFBR1ALDH1A1
SCHEMBL11866190 0.78 TGFBR1 (0.38) TGFBR1ALDH1A1
SCHEMBL25450049 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12146221-B2 Antimicrobial and/or antiviral polymer surfaces and methods for the preparation thereof MOLECULAR PLASMA GROUP S.A. (LU) 2024-11-19 US claimed
CN-114286836-B Antimicrobial and/or antiviral polymeric surfaces 分子等离子集团股份有限公司 2024-08-09 CN claimed
US-20220316064-A1 ANTIMICROBIAL AND/OR ANTIVIRAL POLYMER SURFACES MOLECULAR PLASMA GROUP S.A. (LU) 2022-10-06 US claimed
EP-3987080-A1 ANTIMICROBIAL AND/OR ANTIVIRAL POLYMER SURFACES Molecular Plasma Group SA (LU) 2022-04-27 EP claimed
CN-114286836-A Antimicrobial and/or antiviral polymer surfaces 分子等离子集团股份有限公司 2022-04-05 CN claimed
EP-3574060-B1 EXTENDED SEALING GELS, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF IN SEALING COMPOUNDS FOR SELF-SEALING TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2021-12-22 EP claimed
US-11020915-B2 Extended sealing gels, process for production therof and use therof in sealing compounds for self-sealing tyres ARLANXEO DEUTSCHLAND GMBH (DE) 2021-06-01 US claimed
WO-2020254497-A1 ANTIMICROBIAL AND/OR ANTIVIRAL POLYMER SURFACES WALLQUIST OLOF (CH) 2020-12-24 WO claimed
US-10815364-B2 Sealing gels, process for production thereof and use thereof in sealing compounds for self-sealing tyres ARLANXEO DEUTSCHLAND GMBH (DE) 2020-10-27 US claimed
US-20200123347-A1 DELAYED SEALING COMPOUNDS FOR SELF-SEALING TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2020-04-23 US claimed
EP-3354703-A1 DELAYED SEALING COMPOUNDS FOR SELF-SEALING TYRES ARLANXEO Deutschland GmbH (DE) 2018-08-01 EP claimed
EP-3354702-A1 SEALING COMPOUNDS ARLANXEO Deutschland GmbH (DE) 2018-08-01 EP claimed
EP-3328906-A1 SEALING GELS, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF IN SEALING COMPOUNDS FOR SELF-SEALING TYRES ARLANXEO Deutschland GmbH (DE) 2018-06-06 EP claimed
WO-2017017080-A1 SEALING GELS, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF IN SEALING COMPOUNDS FOR SELF-SEALING TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2017-02-02 WO claimed
EP-3124508-A1 SEALING GELS, METHOD FOR THEIR PREPARATION AS WELL AS THEIR USE IN SEALING COMPOSITIONS FOR SELF-SEALING TIRES ARLANXEO Deutschland GmbH (DE) 2017-02-01 EP claimed
EP-2969021-A1 HAIR CARE COMPOSITIONS COMPRISING POLYELECTROLYTE COMPLEXES FOR DURABLE BENEFITS Isp Investments Inc. (US) 2016-01-20 EP claimed
US-20160008257-A1 HAIR CARE COMPOSITIONS CONTAINING POLYELECTROLYTE COMPLEXES ISP INVESTMENTS INC. (US) 2016-01-14 US claimed
WO-2014144076-A1 HAIR CARE COMPOSITIONS COMPRISING POLYELECTROLYTE COMPLEXES FOR DURABLE BENEFITS ISP INVESTMENTS INC. (US) 2014-09-18 WO claimed
US-20040254290-A1 Glass adhesion promoter AKZO NOBEL N.V. (NL) 2004-12-16 US claimed
EP-0425436-B1 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof CIBA GEIGY AG (CH) 1996-12-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160008257-A1 HAIR CARE COMPOSITIONS CONTAINING POLYELECTROLYTE COMPLEXES POLR1C, PARG, HACD3 TGFBR1 2849/4885ALDH1A1 3395/4885TP53BP1 3791/4885
US-12146221-B2 Antimicrobial and/or antiviral polymer surfaces and methods for the preparation thereof POLI, POLM, PCNA TGFBR1 4623/4885ALDH1A1 4166/4885TP53BP1 2249/4885
US-20220316064-A1 ANTIMICROBIAL AND/OR ANTIVIRAL POLYMER SURFACES POLI, MAVS, POLM TGFBR1 4530/4885ALDH1A1 4156/4885TP53BP1 1977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.