Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALAD | P13716 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648161 | 0.87 | PTGDR2 (0.36) | MCL1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2191688 | 0.78 | RAB9A (0.37) | ALDH1A1LMNARAB9A | |
| SCHEMBL1647383 | 0.77 | HSD17B1 (0.41) | PTPN1RAB9ASMN1; SMN2 | |
| SCHEMBL57513 | 0.76 | DGAT1 (0.41) | ALDH1A1LMNARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16594120 | 0.74 | KMT2A (0.42) | ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1690753 | 0.74 | ESR2 (0.45) | RXRARXRB | |
| SCHEMBL650663 | 0.74 | MAPT (0.45) | HDAC2MCL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5655847 | 0.74 | PTGDR2 (0.38) | ALDH1A1MAPK1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL652037 | 0.72 | HCAR3 (0.44) | ALDH1A1MAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL652038 | 0.72 | HCAR3 (0.44) | ALDH1A1MAPK1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050146-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |