Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648158 | 0.87 | ALAD (0.37) | ALDH1A1SMN1; SMN2MCL1L3MBTL1 | |
| SCHEMBL2191688 | 0.86 | RAB9A (0.37) | PTGDR2C5AR1KDM4EGLAALDH1A1 | |
| SCHEMBL57513 | 0.85 | DGAT1 (0.41) | PTGDR2ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL5655847 | 0.82 | PTGDR2 (0.38) | PTGDR2KDM4EALDH1A1POLBMAPT | |
| SCHEMBL652038 | 0.80 | HCAR3 (0.44) | KDM4EGLAALDH1A1MAPTMEN1 | |
| SCHEMBL652037 | 0.80 | HCAR3 (0.44) | KDM4EGLAALDH1A1MAPTMEN1 | |
| SCHEMBL5657840 | 0.79 | PTGDR2 (0.42) | PTGDR2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16594120 | 0.76 | KMT2A (0.42) | KDM4EALDH1A1POLBMAPTMEN1 | |
| SCHEMBL28885935 | 0.75 | PTGDR2 (0.34) | PTGDR2C5AR1KDM4EGLAALDH1A1 | |
| SCHEMBL16400629 | 0.75 | NCEH1 (0.43) | PTGDR2KDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050146-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |