Sugi Predict

Sugi Predict / Compounds / SCHEMBL1648352

SCHEMBL1648352

SCHEMBL1648352

CC(C)(C)c1ccc(OP(Cl)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APEX1 P27695 1/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ CYP2C19 P33261 1/20 0.37
▸ KDM4E B2RXH2 4/20 0.36
▸ ALDH1A1 P00352 4/20 0.35
▸ HPGD P15428 2/20 0.35
▸ ALOX15 P16050 2/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ MAPT P10636 3/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ RXRG P48443 1/20 0.33
▸ GAA P10253 2/20 0.32
▸ RECQL P46063 2/20 0.32
▸ MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19000756 0.93 KDM4E (0.42) APEX1CA1CA2CA9CYP2C19
SCHEMBL9068739 0.92 APEX1 (0.36) APEX1CA1CA2CA9CYP2C19
SCHEMBL9171615 0.89 ALDH1A1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL9347144 0.86 APEX1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL20696111 0.85 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL29349873 0.85 CA1 (0.41) APEX1CA1CA2CA9CYP2C19
SCHEMBL9347011 0.85 CA1 (0.41) APEX1CA1CA2CA9CYP2C19
SCHEMBL26607 0.85 CA1 (0.41) APEX1CA1CA2CA9CYP2C19
SCHEMBL19020197 0.84 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL30267754 0.84 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0374761-B1 PROCESS FOR THE PREPARATION OF ORGANOPHOSPHORUS COMPOUNDS OF 4,4-DIORGANOMAGNESIUM BIPHENYL, AND USE OF ORGANOPHOSPHORUS COMPOUNDS AS STABILIZERS FOR POLYMERS, PARTICULARLY POLYOLEFINE MOULDING COMPOSITIONS HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-05 — — EP claimed
CN-114057548-B Method for recovering 2, 4-di-tert-butylphenol from concentrated mother liquor of antioxidant 168 陕西艾科莱特新材料有限公司 2024-03-01 — — CN disclosed
CN-116947606-A Method for recovering 2, 4-di-tert-butylphenol from antioxidant 168 mother liquor 营口风光新材料股份有限公司 2023-10-27 — — CN disclosed
CN-114057548-A Method for recovering 2, 4-di-tert-butylphenol from antioxidant 168 concentrated mother liquor 陕西艾科莱特新材料有限公司 2022-02-18 — — CN disclosed
CN-108070001-B Bisphosphites having a 2, 4-tert-butylphenyl unit and their use as ligands in hydroformylation 赢创运营有限公司 2020-10-13 — — CN disclosed
US-10011619-B2 Process for reducing the chlorine content of organotetraphosphites EVONIK DEGUSSA GMBH (DE) 2018-07-03 — — US disclosed
US-20180127444-A1 BISPHOSPHITES HAVING 2,4-TERT-BUTYLPHENYL UNITS AND USE THEREOF AS LIGANDS IN HYDROFORMYLATION EVONIK DEGUSSA GMBH (DE) 2018-05-10 — — US disclosed
US-9908910-B2 Bidentate diphosphoramidites with a piperazine group as ligands for hydroformylation EVONIK DEGUSSA GMBH (DE) 2018-03-06 — — US disclosed
US-9908910-B2 Bidentate diphosphoramidites with a piperazine group as ligands for hydroformylation EVONIK DEGUSSA GMBH (DE) 2018-03-06 — — US disclosed
US-9896404-B2 Bidentate diphosphoramidites with a homopiperazine group as ligands for hydroformylation EVONIK DEGUSSA GMBH (DE) 2018-02-20 — — US disclosed
US-5210260-A PROCESS FOR OBTAINING BIS(2,4-DI-TERT-BUTYLPHENYL) HALOPHOSPHITES HOECHST AG (DE) 1993-05-11 — — US disclosed
US-5109043-A Reacting 4,4'-dihalobiphenyl with suspension of finely divided magnesium to form grignard reagent HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-28 — — US disclosed
US-5109043-A Reacting 4,4'-dihalobiphenyl with suspension of finely divided magnesium to form grignard reagent HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-28 — — US disclosed
US-5061818-A Fluorination with metal or ammonium fluoride in presence of pyridine halide salt ETHYL CORPORATION (US) 1991-10-29 — — US disclosed
EP-0374761-A1 Process for the preparation of organophosphorus compounds of 4,4-diorganomagnesium biphenyl, and use of organophosphorus compounds as stabilizers for polymers, particularly polyolefine moulding compositions HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 — — EP disclosed
EP-0358985-A1 Method of transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1990-03-21 — — EP disclosed
EP-0312915-A2 Process for making cyclic aryl chlorophosphites ETHYL CORPORATION (US) 1989-04-26 — — EP disclosed
EP-0312790-A2 Process for transhalogenating a halophosphorus compound with fluoride ETHYL CORPORATION (US) 1989-04-26 — — EP disclosed
US-4739000-A FOR ORGANIC POLYMERS ETHYL CORPORATION (US) 1988-04-19 — — US disclosed
US-4724247-A NONHYDROLYZING; POLYMER STABILIZERS ETHYL CORPORATION (US) 1988-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011619-B2 Process for reducing the chlorine content of organotetraphosphites DCPS, DDT, TET2 APEX1 2071/4885CA1 665/4885CA2 356/4885
US-20180127444-A1 BISPHOSPHITES HAVING 2,4-TERT-BUTYLPHENYL UNITS AND USE THEREOF AS LIGANDS IN HYDROFORMYLATION BPGM, NUDT1, PHPT1 APEX1 354/4885CA1 1923/4885CA2 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.