SCHEMBL649648

SCHEMBL649648

O=C(Nc1ccccc1)c1cc(Cl)c(Cl)c(Cl)c1OCl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.49
TMPRSS4 Q9NRS4 1/20 0.49
GPR27 Q9NS67 3/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
LMNA P02545 2/20 0.47
TP53 P04637 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP2C19 P33261 1/20 0.47
THPO P40225 1/20 0.47
MTOR P42345 1/20 0.47
RORC P51449 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15568158 0.99 PPARG (0.48) PPARGTMPRSS4GPR27MEN1KMT2A
Potassium SCHEMBL15568160 0.99 PPARG (0.48) PPARGTMPRSS4GPR27MEN1KMT2A
Salicylanilide SCHEMBL27837552 0.92 MEN1 (0.60) TMPRSS4MEN1KMT2ALMNATP53
SCHEMBL1648370 0.84 GPR27 (0.53) PPARGTMPRSS4GPR27MEN1KMT2A
SCHEMBL8009293 0.83 PPARG (0.58) PPARGTMPRSS4GPR27MEN1KMT2A
SCHEMBL2296409 0.80 TMPRSS4 (0.56) PPARGTMPRSS4GPR27MEN1KMT2A
SCHEMBL8469266 0.79 SMO (0.56) MEN1KMT2ALMNATP53CYP2C9
SCHEMBL7761587 0.79 GPR27 (0.47) TMPRSS4GPR27MEN1KMT2AMAPT
SCHEMBL28017780 0.78 SMO (0.55) MEN1KMT2ALMNATP53CYP2C9
SCHEMBL7760288 0.77 CHRNB2 (0.55) TMPRSS4MEN1KMT2ATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 767 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323279-A1 MUTANT ALGAE, METHOD OF PREPARATION AND APPLICATION THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2023-10-12 US claimed
WO-2023148531-A1 SMALL MOLECULES FOR USE IN PREVENTING AND/OR TREATMENT OF NEURODEGENERATIVE DISEASES TOXFINDER, LDA (PT) 2023-08-10 WO claimed
CN-115974346-A Sludge reduction agent and preparation method thereof 广州沣凌环保技术有限公司 2023-04-18 CN claimed
CN-111825301-B Decoupling agent 3,3 ', 4', 5-tetrachlorosalicylanilide-based method for enhancing sludge dewatering process 哈尔滨工业大学 2022-04-22 CN claimed
US-20210379087-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2021-12-09 US claimed
US-11166926-B2 Compositions and methods for protecting a host from enteric toxigenic pathogens THE HOSPITAL FOR SICK CHILDREN (CA) 2021-11-09 US claimed
CN-109133379-B Method for promoting activation and regeneration of sewage treatment biological membrane 中冶华天工程技术有限公司 2021-08-24 CN claimed
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
CN-111825301-A Decoupling agent 3,3 ', 4', 5-tetrachlorosalicylanilide-based method for enhancing sludge dewatering process 哈尔滨工业大学 2020-10-27 CN claimed
CN-111526873-A Substituted tolanes for regulating microbial colonization 生物曼迪克斯有限责任公司 2020-08-11 CN claimed
CN-1228797-A Antibacterial solid surface materials DU PONT (US) 1999-09-15 CN claimed
EP-0904318-A1 ANTIBACTERIAL SOLID SURFACE MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-03-31 EP claimed
EP-0868756-A1 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-10-07 EP claimed
EP-0856735-A1 Colour staining reagent for blood cells ABX (FR) 1998-08-05 EP claimed
WO-1998013887-A1 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-04-02 WO claimed
US-5731105-A Battery electrochemical cell with a non-liquid electrolyte E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-03-24 US claimed
WO-1997049870-A1 ANTI-CORROSIVE MATERIAL FULTON ENTERPRISES, INC. (US) 1997-12-31 WO claimed
WO-1997049761-A1 ANTIBACTERIAL SOLID SURFACE MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-31 WO claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
US-5370876-A Aqueous cream containing alkali metal fatty acid salt, microbiocide, polyol emollient, alkali metal silicate MICROBARRIERS (US) 1994-12-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230323279-A1 MUTANT ALGAE, METHOD OF PREPARATION AND APPLICATION THEREOF STOM, PPA1, ALAD PPARG 1890/4885TMPRSS4 4158/4885GPR27 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.