SCHEMBL224947

SCHEMBL224947

Brc1ccc(SSc2ccc(Br)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.57
FBP1 P09467 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
MGLL Q99685 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MAOA P21397 4/20 0.44
MAOB P27338 4/20 0.44
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.42
MAPK1 P28482 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
HAO1 Q9UJM8 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TSHR P16473 1/20 0.36
CES2 O00748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28293836 0.97 CYP2A6 (0.53) CYP2A6FBP1SMN1; SMN2MAPTHPGD
SCHEMBL10899441 0.91 MAOA (0.56) CYP2A6FBP1SMN1; SMN2MAPTHPGD
SCHEMBL19735872 0.86 ALDH1A1 (0.68) CYP2A6FBP1MAOAMAOBALDH1A1
SCHEMBL27923318 0.84 FBP1 (0.42) CYP2A6FBP1SMN1; SMN2MAPTHPGD
SCHEMBL13430122 0.84 FBP1 (0.42) CYP2A6FBP1SMN1; SMN2MAPTHPGD
SCHEMBL13430067 0.84 MAOB (0.50) CYP2A6FBP1SMN1; SMN2MAPTHPGD
SCHEMBL13430073 0.84 CYP2C19 (0.48) CYP2A6FBP1MAPTHPGDMAOA
SCHEMBL942981 0.84 MAPT (0.56) CYP2A6FBP1MAPTMAOAMAOB
SCHEMBL26194809 0.82 CYP2A6 (0.44) CYP2A6FBP1SMN1; SMN2MAOAMAOB
SCHEMBL19718024 0.80 MAOA (0.43) CYP2A6FBP1SMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945964-A Synthesis method of aryl alkyl asymmetric thioether 中国人民解放军军事科学院防化研究院 2024-04-30 CN claimed
CN-114057782-B Process method for synthesizing 4-mercaptophenylboronic acid 大连双硼医药化工有限公司 2024-02-27 CN claimed
CN-114057782-A Process method for synthesizing 4-mercapto phenylboronic acid 大连双硼医药化工有限公司 2022-02-18 CN claimed
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US claimed
JP-54144331-A None JP disclosed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-12600837-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
EP-4527473-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2026-03-25 EP disclosed
US-12544628-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
EP-0043788-A1 Imidazole derivatives, process for their preparation and their pharmaceutical compositions SCHERING AKTIENGESELLSCHAFT (DE) 1982-01-13 EP disclosed
JP-S54144331-A P'-CYANOPHENYL P-(BETA-ALKOXY)ETHYLTHIO-BENZOATE CHISSO CORP 1979-11-10 JP disclosed
US-4162259-A ANTIBACTERIAL, ANTIMICROBIAL, PHARMACOKINETIC Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske fabrik Produktionsaktienselskab) (DK) 1979-07-24 US disclosed
US-4100276-A BACTERICIDES, MICROBIOCIDES LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1978-07-11 US disclosed
US-4029706-A Reduction with polymeric reagent DYNAPOL (US) 1977-06-14 US disclosed
US-4027090-A SYNERGISTIC MOLECULAR WEIGHT CONTROL STANDARD OIL COMPANY (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544628-B2 Golf ball KIF5A, KIF5C, SURF4 CYP2A6 3227/4885FBP1 3635/4885SMN1; SMN2 1272/4885
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 CYP2A6 4080/4885FBP1 4713/4885SMN1; SMN2 471/4885
US-12600837-B2 Rubber composition and crosslinked rubber molded product RER1, RIF1, SHC1 CYP2A6 4552/4885FBP1 1754/4885SMN1; SMN2 627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.