SCHEMBL16484448

SCHEMBL16484448

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(-c4ccc(N(c5ccccc5)c5ccc(-c6ccccn6)nc5)cc4)c4cccc-3c24)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGDS O60760 2/20 0.36
▸ TGFBR1 P36897 2/20 0.34
▸ CYP11B1 P15538 1/20 0.34
▸ LMNA P02545 4/20 0.33
▸ SMN1; SMN2 Q16637 3/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ CASP3 P42574 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33
▸ KDR P35968 1/20 0.31
▸ TNF P01375 1/20 0.31
▸ GRM5 P41594 1/20 0.31
▸ KDM4E B2RXH2 3/20 0.31
▸ TP53 P04637 2/20 0.31
▸ ALOX15 P16050 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ L3MBTL1 Q9Y468 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17012236 0.94 TGFBR1 (0.34) HPGDSTGFBR1CYP11B1LMNASMN1; SMN2
SCHEMBL16484417 0.92 NPC1 (0.35) TGFBR1CYP11B1LMNASMN1; SMN2NPC1
SCHEMBL16484420 0.91 CYP11B1 (0.38) HPGDSCYP11B1TNFENPP1
SCHEMBL16484465 0.91 NPC1 (0.36) TGFBR1CYP11B1LMNASMN1; SMN2NPC1
SCHEMBL16484419 0.90 PDK2 (0.36) TGFBR1LMNASMN1; SMN2NPC1HPGD
SCHEMBL16485343 0.90 HPGDS (0.37) HPGDSTGFBR1CYP11B1LMNASMN1; SMN2
SCHEMBL20016891 0.89 CYP11B1 (0.33) HPGDSTGFBR1CYP11B1PDK2
SCHEMBL16484468 0.88 PDK2 (0.34) TGFBR1LMNASMN1; SMN2NPC1HPGD
SCHEMBL17012345 0.88 CYP11B1 (0.40) CYP11B1HPGDTNFKDM4EMAPK1
SCHEMBL11992142 0.88 HPGDS (0.42) HPGDSTGFBR1LMNASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed
WO-2014057874-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT 東レ株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 HPGDS 4604/4885TGFBR1 2930/4885CYP11B1 4354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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