SCHEMBL17012236

SCHEMBL17012236

c1ccc(-c2c3c(c(-c4ccccc4)c4ccccc24)-c2ccc(-c4cccc(N(c5ccccc5)c5ccc(-c6ccccn6)nc5)c4)c4cccc-3c24)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGFBR1 P36897 7/20 0.34
▸ WNT1 P04628 1/20 0.33
▸ HPGDS O60760 1/20 0.33
▸ GRM5 P41594 1/20 0.32
▸ PIM1 P11309 2/20 0.32
▸ PRKDC P78527 1/20 0.31
▸ DCTPP1 Q9H773 1/20 0.31
▸ CYP11B1 P15538 1/20 0.31
▸ FEN1 P39748 1/20 0.31
▸ LMNA P02545 2/20 0.30
▸ HPGD P15428 2/20 0.30
▸ TSHR P16473 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ CASP3 P42574 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484448 0.94 HPGDS (0.36) TGFBR1HPGDSGRM5CYP11B1LMNA
SCHEMBL20016891 0.93 CYP11B1 (0.33) TGFBR1HPGDSCYP11B1
SCHEMBL16485097 0.92 PRKDC (0.35) TGFBR1GRM5PRKDCDCTPP1LMNA
SCHEMBL16485096 0.92 TGFBR1 (0.35) TGFBR1GRM5PRKDCDCTPP1CYP11B1
SCHEMBL17132477 0.92 TGFBR1 (0.35) TGFBR1GRM5PRKDCDCTPP1CYP11B1
SCHEMBL16485074 0.91 CYP11B1 (0.35) CYP11B1
SCHEMBL17012324 0.91 TGFBR1 (0.36) TGFBR1WNT1HPGDSGRM5PIM1
SCHEMBL16484419 0.90 PDK2 (0.36) TGFBR1GRM5PIM1PRKDCDCTPP1
SCHEMBL16485105 0.89 PRKDC (0.36) TGFBR1GRM5PRKDCDCTPP1LMNA
SCHEMBL16485082 0.89 CYP11B1 (0.36) TGFBR1WNT1CYP11B1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed
US-9935273-B2 Fluoranthene derivative, light-emitting device material containing same, and light-emitting device TORAY INDUSTRIES, INC. (JP) 2018-04-03 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2015-10-01 — — US disclosed
EP-2907803-A1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT Toray Industries, Inc. (JP) 2015-08-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280139-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING DEVICE MATERIAL CONTAINING SAME, AND LIGHT-EMITTING DEVICE FMNL1, AFF2, LEF1 TGFBR1 2930/4885WNT1 200/4885HPGDS 4604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback