Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5073799 | 0.72 | MEN1 (0.41) | MEN1KMT2AHTR3EHTR3BCYP1A2 | |
| SCHEMBL19185898 | 0.70 | MEN1 (0.50) | MEN1KMT2AHTR3EHTR3BCYP1A2 | |
| SCHEMBL18136 | 0.70 | GABRA1 (0.56) | MEN1KMT2AGAAGABRA1GABRB2 | |
| SCHEMBL3801597 | 0.69 | MEN1 (0.39) | MEN1KMT2AHTR3EHTR3BCYP1A2 | |
| SCHEMBL5073795 | 0.67 | MEN1 (0.42) | MEN1KMT2AHTR3EHTR3BCYP1A2 | |
| SCHEMBL2457516 | 0.66 | MEN1 (0.49) | MEN1KMT2AHTR3EHTR3BCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL1479416 | 0.66 | KEAP1 (0.46) | MEN1KMT2AGAABRD9ALDH1A1 | |
| SCHEMBL11506767 | 0.66 | GAA (0.72) | MEN1KMT2AHTR3EHTR3BCYP1A2 | |
| SCHEMBL1570705 | 0.66 | GABRA1 (0.47) | MEN1KMT2ATSHRGAAGABRA1 | |
| SCHEMBL2362269 | 0.65 | GABRA1 (0.61) | MEN1KMT2ACYP1A2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047981-A1 | USE OF A DIALKYLPHENYL-4-AMINOPIPERIDINE AS AGENT FOR THE TREATMENT OF HUMAN PERSPIRATION; NOVEL COMPOUNDS AND COMPOSITIONS COMPRISING THEM | L'OREAL (FR) | 2011-04-28 | — | — | WO | claimed |
| WO-2011047981-A1 | USE OF A DIALKYLPHENYL-4-AMINOPIPERIDINE AS AGENT FOR THE TREATMENT OF HUMAN PERSPIRATION; NOVEL COMPOUNDS AND COMPOSITIONS COMPRISING THEM | L'OREAL (FR) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011047981-A1 | USE OF A DIALKYLPHENYL-4-AMINOPIPERIDINE AS AGENT FOR THE TREATMENT OF HUMAN PERSPIRATION; NOVEL COMPOUNDS AND COMPOSITIONS COMPRISING THEM | L'OREAL (FR) | 2011-04-28 | — | — | WO | disclosed |