Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486743 | 0.81 | PNP (0.39) | ALDH1A1CYP2D6ATMSMN1; SMN2MAPT | |
| SCHEMBL1422153 | 0.76 | ALDH1A1 (0.47) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL1422155 | 0.74 | MAPT (0.51) | ALDH1A1CYP2D6ATMLMNASMN1; SMN2 | |
| SCHEMBL16486490 | 0.74 | HRH4 (0.44) | MPO | |
| SCHEMBL8124628 | 0.71 | PNP (0.43) | ALDH1A1CYP2D6LMNAPOLBMPO | |
| SCHEMBL6941905 | 0.71 | ALDH1A1 (0.50) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL7097439 | 0.70 | ALDH1A1 (0.73) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| Iodide SCHEMBL9053765 | 0.69 | PNP (0.41) | ALDH1A1CYP2D6LMNAPOLBMPO | |
| Hydrochloric Acid SCHEMBL7522555 | 0.69 | ALDH1A1 (0.68) | ALDH1A1CYP2D6ATMNPSR1LMNA | |
| SCHEMBL23612255 | 0.69 | ALDH1A1 (0.82) | ALDH1A1CYP2D6ATMNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |