Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | MGAM | O43451 | 6/20 | 0.44 |
| ▸ | SI | P14410 | 6/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12171947 | 0.75 | ATR (0.49) | ATRPIK3CDASH1LALDH1A1RAB9A | |
| SCHEMBL12419574 | 0.73 | NPC1 (0.52) | GAAMGAMSIMGAM2ASH1L | |
| SCHEMBL12419559 | 0.73 | RAB9A (0.53) | GAAALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL2816834 | 0.72 | NPC1 (0.65) | GAAALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL12419575 | 0.72 | ALDH1A1 (0.44) | GAAALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL29954839 | 0.69 | HPGDS (0.54) | PIK3CDPIK3CBPIK3CGASH1L | |
| SCHEMBL12419558 | 0.69 | STIM1 (0.39) | GAAALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL12508694 | 0.69 | SMN1; SMN2 (0.66) | GAAALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL12420282 | 0.68 | RAB9A (0.36) | GAAALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL12419567 | 0.68 | PARP1 (0.37) | GAAALDH1A1RAB9AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150368278-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2015-12-24 | — | — | US | disclosed |
| US-8957049-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368278-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ASAH1 | ATR 4840/4885GAA 344/4885MGAM 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.