Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606119 | 0.98 | ADRA2A (0.53) | ADRA2AHTR6 | |
| SCHEMBL25645586 | 0.97 | ADRA2A (0.51) | ADRA2AHTR6 | |
| SCHEMBL11470450 | 0.97 | ADRA2A (0.51) | ADRA2AHTR6 | |
| SCHEMBL3764570 | 0.93 | HTR6 (0.54) | HTR6 | |
| SCHEMBL16488227 | 0.93 | HTR6 (0.54) | HTR6 | |
| Hydrochloric Acid SCHEMBL28216900 | 0.91 | HTR6 (0.55) | HTR6 | |
| Ammonia Solution, Strong SCHEMBL29771408 | 0.84 | HTR1D (0.49) | HTR6 | |
| SCHEMBL9963995 | 0.81 | SLC18A2 (0.68) | ADRA2A | |
| SCHEMBL4278447 | 0.81 | CHRNB2 (0.49) | ADRA2AHTR6 | |
| SCHEMBL8106512 | 0.81 | ADRA2A (0.47) | ADRA2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170865-A2 | NOVEL SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF, AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009010660-A2 | SUBSTITUTED INDAZOLES, THE PREPARATION THEREOF, AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-01-22 | — | — | WO | disclosed |