SCHEMBL2606119

SCHEMBL2606119

CN1CCCCC1Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ADRA2A P08913 1/20 0.53
▸ HTR6 P50406 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25645586 0.98 ADRA2A (0.51) ADRA2AHTR6
SCHEMBL11470450 0.98 ADRA2A (0.51) ADRA2AHTR6
Ammonia Solution, Strong SCHEMBL3645001 0.98 ADRA2A (0.51) ADRA2AHTR6
SCHEMBL3764570 0.95 HTR6 (0.54) HTR6
SCHEMBL16488227 0.95 HTR6 (0.54) HTR6
Hydrochloric Acid SCHEMBL28216900 0.93 HTR6 (0.55) HTR6
SCHEMBL4278447 0.83 CHRNB2 (0.49) ADRA2AHTR6
SCHEMBL9963995 0.83 SLC18A2 (0.68) ADRA2A
SCHEMBL8106512 0.83 ADRA2A (0.47) ADRA2AHTR6
Ammonia Solution, Strong SCHEMBL29771408 0.81 HTR1D (0.49) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 — — US claimed
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 — — US disclosed
EP-4164481-B1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2024-10-16 — — EP disclosed
CN-117700657-A Poly (4-aryl) piperidine polymer, preparation method and prepared anion exchange membrane 西湖大学 2024-03-15 — — CN disclosed
US-20230337934-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2023-10-26 — — US disclosed
WO-2023107557-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2023-06-15 — — WO disclosed
US-20230183224-A1 BEZOXAZINE DERIVATIVES USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2023-06-15 — — US disclosed
EP-4164481-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH Nanose Medical Ltd (IL) 2023-04-19 — — EP disclosed
US-20220317122-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION RESPIRATION SCAN LTD. (IL) 2022-10-06 — — US disclosed
EP-4013302-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION Respiration Scan Ltd (IL) 2022-06-22 — — EP disclosed
US-20110015178-A1 Amido-Thiophene Compounds and Their Use THE UNIVERSITY OF EDINBURGH (GB) 2011-01-20 — — US disclosed
WO-2010146338-A1 AMIDO-ISOTHIAZOLE COMPOUNDS AND THEIR USE AS INHIBITORS OF 11BETA-HSD1 FOR THE TREATMENT OF METABOLIC SYNDROME AND RELATED DISORDERS THE UNIVERSITY OF EDINBURGH (GB) 2010-12-23 — — WO disclosed
WO-2009112845-A1 AMIDO-THIOPHENE COMPOUNDS AND THEIR USE THE UNIVERSITY OF EDINBURGH (GB) 2009-09-17 — — WO disclosed
US-7459460-B2 Trisubstituted heteroaromatic compounds as calcium sensing receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2008-12-02 — — US disclosed
WO-2008062235-A1 THERAPEUTIC G-QUADRUPLEX LIGANDS SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) 2008-05-29 — — WO disclosed
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 — — US disclosed
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 — — US disclosed
US-7205311-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED 2007-04-17 — — US disclosed
US-7205311-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED 2007-04-17 — — US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183224-A1 BEZOXAZINE DERIVATIVES USEFUL AS MONOACYLGLYCEROL LIPASE INHIBITORS LPL, LIPC, PNLIP ADRA2A 1046/4885HTR6 4422/4885
US-20110015178-A1 Amido-Thiophene Compounds and Their Use HSD11B1, HSD11B2, HSD17B1 ADRA2A 1565/4885HTR6 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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