SCHEMBL25645586

SCHEMBL25645586

CN1CCCCCCC1Cc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.51
HTR6 P50406 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11470450 1.00 ADRA2A (0.51) ADRA2AHTR6
SCHEMBL2606119 0.98 ADRA2A (0.53) ADRA2AHTR6
Ammonia Solution, Strong SCHEMBL3645001 0.97 ADRA2A (0.51) ADRA2AHTR6
SCHEMBL3764570 0.93 HTR6 (0.54) HTR6
SCHEMBL16488227 0.93 HTR6 (0.54) HTR6
Hydrochloric Acid SCHEMBL28216900 0.91 HTR6 (0.55) HTR6
SCHEMBL11473707 0.83 ALDH1A1 (0.49) ADRA2AHTR6
SCHEMBL11474181 0.83 DRD2 (0.48) ADRA2AHTR6
SCHEMBL11486228 0.83 CHRNB2 (0.48) ADRA2AHTR6
SCHEMBL11472033 0.82 DRD2 (0.53) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107557-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2023-06-15 WO disclosed