Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16488564 | 0.84 | DHODH (0.42) | DHODHMEN1KMT2AAKR1C3FABP1 | |
| SCHEMBL16488681 | 0.83 | DHODH (0.53) | DHODHMEN1KMT2AKMOCYP2C8 | |
| SCHEMBL16488560 | 0.82 | RXRA (0.50) | DHODHFABP1 | |
| SCHEMBL16488563 | 0.82 | RXRA (0.50) | DHODHFABP1 | |
| SCHEMBL25551247 | 0.80 | RXRA (0.46) | DHODHMEN1KMT2AMAPK1 | |
| SCHEMBL16488557 | 0.80 | ERN1 (0.34) | DHODHMEN1KMT2AAKR1C3TTR | |
| SCHEMBL16488559 | 0.80 | BRD4 (0.36) | DHODHAKR1C3TTR | |
| SCHEMBL12349931 | 0.80 | CA12 (0.42) | MEN1KMT2AAKR1C3TTRMAPK1 | |
| SCHEMBL15119805 | 0.80 | RXRA (0.56) | DHODH | |
| SCHEMBL12384276 | 0.78 | MEN1 (0.44) | MEN1KMT2AAKR1C3TTRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593132-B2 | Metal-organic frameworks (MOF) for gas capture | THE UNIVERSITY OF NOTTINGHAM (GB) | 2017-03-14 | — | — | US | disclosed |
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | THE UNIVERSITY OF NOTTINGHAM (GB) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | HAO2, TRPM6, FTH1 | DHODH 641/4885MEN1 3128/4885KMT2A 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.