Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.44 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075326 | 0.91 | DHODH (0.46) | DHODHKMOTSHRTDP1L3MBTL1 | |
| SCHEMBL29908924 | 0.86 | DHODH (0.57) | DHODHKMODAOTSHRNAPRT | |
| SCHEMBL29908910 | 0.84 | DHODH (0.55) | DHODHKMODAOTSHRNAPRT | |
| SCHEMBL16488558 | 0.83 | DHODH (0.41) | DHODHKMOTTRPTPRCCYP2C8 | |
| SCHEMBL29644549 | 0.83 | DHODH (0.53) | DHODHKMODAOTSHRNAPRT | |
| SCHEMBL10009333 | 0.83 | DHODH (0.53) | DHODHKMODAOTSHRNAPRT | |
| SCHEMBL18688870 | 0.82 | EGFR (0.65) | DHODHKMODAOTSHRNAPRT | |
| SCHEMBL31658243 | 0.82 | EGFR (0.65) | DHODHKMODAOTSHRNAPRT | |
| SCHEMBL29895711 | 0.80 | TTR (0.55) | DHODHKMOTTRTDP1L3MBTL1 | |
| SCHEMBL28375588 | 0.80 | KDM4E (0.46) | DHODHKMOATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593132-B2 | Metal-organic frameworks (MOF) for gas capture | THE UNIVERSITY OF NOTTINGHAM (GB) | 2017-03-14 | — | — | US | disclosed |
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | THE UNIVERSITY OF NOTTINGHAM (GB) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150047505-A1 | METAL-ORGANIC FRAMEWORKS (MOF) FOR GAS CAPTURE | HAO2, TRPM6, FTH1 | DHODH 641/4885KMO 1675/4885DAO 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.