SCHEMBL1648859

SCHEMBL1648859

C=C(C)C1C=CC(=O)CC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NLRP3 Q96P20 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23675052 1.00 CYP2C19 (0.33) CYP2C19LMNATSHRTRPA1ALDH1A1
SCHEMBL25217392 0.81
SCHEMBL13425089 0.79 NFKB1 (0.31) NLRP3
SCHEMBL8096482 0.77 ALOX15 (0.39) LMNAALDH1A1ALOX15CYP1B1
SCHEMBL2083008 0.75 POLB (0.33) NLRP3
SCHEMBL2598725 0.73 CYP1A2 (0.38) ALDH1A1KMT2ANLRP3
SCHEMBL681879 0.69
SCHEMBL3983475 0.69
SCHEMBL767441 0.69
SCHEMBL18709794 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486226-B2 Cannabinoid derivatives REVVITY HEALTH SCIENCES, INC. (US) 2025-12-02 US disclosed
US-20210230113-A1 CANNABINOID DERIVATIVES REVVITY HEALTH SCIENCES, INC. 2021-07-29 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
US-8389534-B2 Pyrimidine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-03-05 US disclosed
US-8389534-B2 Pyrimidine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-03-05 US disclosed
US-20100298579-A1 Process for preparing synthetic cannabinoids THC PHARM GMBH (DE) 2010-11-25 US disclosed
WO-2010045379-A2 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) 2010-04-22 WO disclosed
WO-2010045379-A2 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) 2010-04-22 WO disclosed
WO-2010045377-A2 PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) 2010-04-22 WO disclosed
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069634-A1 PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069634-A1 PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed
US-20100069634-A1 PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2010-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486226-B2 Cannabinoid derivatives CNR2, CNR1, CDIPT CYP2C19 308/4885LMNA 2943/4885TSHR 2519/4885
US-20210230113-A1 CANNABINOID DERIVATIVES CNR2, CNR1, CDIPT CYP2C19 308/4885LMNA 2943/4885TSHR 2519/4885
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CYP2C19 423/4885LMNA 3761/4885TSHR 708/4885
US-20100069634-A1 PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, GPR18 CYP2C19 667/4885LMNA 4090/4885TSHR 964/4885
US-20100298579-A1 Process for preparing synthetic cannabinoids CNR2, CNR1, FAAH CYP2C19 33/4885LMNA 4195/4885TSHR 3776/4885
US-20100069440-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CYP2C19 423/4885LMNA 3761/4885TSHR 708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.