SCHEMBL29908910

SCHEMBL29908910

O=C(O)c1cc(C(=O)O)cc(-c2ccccc2-c2ccccc2-c2cc(C(=O)O)cc(C(=O)O)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.55
KMO O15229 1/20 0.52
PTPRC P08575 2/20 0.52
PTGER1 P34995 2/20 0.51
DAO P14920 1/20 0.50
TSHR P16473 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TTR P02766 4/20 0.48
SRD5A2 P31213 2/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
SRD5A1 P18405 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29908924 0.98 DHODH (0.57) DHODHKMOPTPRCPTGER1DAO
SCHEMBL28910860 0.85 DHODH (0.50) DHODHKMODAOTSHRNAPRT
SCHEMBL6849600 0.85 ALDH1A1 (0.56) DHODHKMOPTPRCDAOTSHR
SCHEMBL16488681 0.84 DHODH (0.53) DHODHKMOPTPRCDAOTSHR
SCHEMBL15124553 0.84 CYP2A6 (0.54) DHODHKMOTSHRTTRKMT2A
SCHEMBL28719966 0.84 NR1H4 (0.56) DHODHKMOTTR
SCHEMBL1707626 0.83 KMO (0.70) KMOPTPRCPTGER1DAOTSHR
SCHEMBL29895711 0.82 TTR (0.55) DHODHKMOPTPRCTTRSRD5A2
SCHEMBL1768904 0.81 DHODH (0.77) DHODHKMODAOTSHRNAPRT
Isophthalic Acid SCHEMBL9679148 0.81 DAO (0.62) KMOPTPRCDAOTSHRNAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 US disclosed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP disclosed
US-20240157304-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2024-05-16 US disclosed
US-20240149223-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2024-05-09 US disclosed
EP-4304765-A1 SPACER FOR A SPIRAL WOUND MEMBRANE Evove Ltd (GB) 2024-01-17 EP disclosed
EP-4304766-A1 MEMBRANE DEVICE Evove Ltd (GB) 2024-01-17 EP disclosed
WO-2022189793-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2022-09-15 WO disclosed
WO-2022189785-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2022-09-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 DHODH 2238/4885KMO 4412/4885PTPRC 4050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.