Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 12/20 | 0.41 |
| ▸ | CNR1 | P21554 | 8/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15304550 | 0.97 | THRB (0.44) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL16490256 | 0.90 | THRB (0.45) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL10606320 | 0.89 | CNR2 (0.48) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL8853777 | 0.88 | THRB (0.46) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL19650671 | 0.86 | CNR2 (0.52) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL18719339 | 0.84 | THRB (0.47) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL14499815 | 0.82 | THRB (0.53) | THRBMEN1KMT2ATDP1APEX1 | |
| SCHEMBL18719346 | 0.82 | CNR2 (0.46) | MEN1KMT2ATDP1CNR2CNR1 | |
| SCHEMBL18719349 | 0.82 | CNR2 (0.46) | CNR2CNR1TSHRNR1H2NR1H3 | |
| SCHEMBL18733989 | 0.82 | THRB (0.48) | THRBMEN1KMT2ATDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9364403-B2 | Hair treatment methods | PERACHEM LIMITED (GB) | 2016-06-14 | — | — | US | disclosed |
| US-9320695-B2 | Hair treatment methods | PERACHEM LIMITED (GB) | 2016-04-26 | — | — | US | disclosed |
| US-20150068548-A1 | Hair Treatment Methods | HSNF LIMITED (GB) | 2015-03-12 | — | — | US | disclosed |
| US-20150047131-A1 | Hair Treatment Methods | HSNF LIMITED (GB) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150068548-A1 | Hair Treatment Methods | TST, OAT, SLC14A1 | THRB 2423/4885MEN1 3002/4885KMT2A 2377/4885 |
| US-20150047131-A1 | Hair Treatment Methods | POLR1C, SHH, DNMT3A | THRB 2412/4885MEN1 2294/4885KMT2A 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.