Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198016 | 0.81 | TSHR (0.46) | TSHRHTTHTR6POLBGAA | |
| SCHEMBL16495124 | 0.80 | HTR2A (0.49) | TSHRHTTHTR6POLBGAA | |
| SCHEMBL3166437 | 0.79 | HTT (0.47) | TSHRHTTHTR6ALDH1A1KMT2A | |
| SCHEMBL709683 | 0.78 | TSHR (0.62) | TSHRHTTHTR6POLBGAA | |
| SCHEMBL16495095 | 0.76 | GAA (0.51) | HTTERN1HTR6GAAALDH1A1 | |
| SCHEMBL2350373 | 0.76 | AKR1B1 (0.51) | HTR6POLBGAAGFERALDH1A1 | |
| SCHEMBL16810 | 0.76 | HSD11B1 (0.57) | HTR6POLBGAAGFERKIF18A | |
| SCHEMBL229081 | 0.75 | HTR6 (0.48) | TSHRHTTHTR6POLBGAA | |
| SCHEMBL226516 | 0.75 | HTR6 (0.48) | HTR6POLBGAAGFERALDH1A1 | |
| SCHEMBL4752052 | 0.75 | KMT2A (0.50) | TSHRHTTERN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |