Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NAT1 | P18440 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742902 | 0.85 | MMP2 (0.39) | HTR6KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL226516 | 0.85 | HTR6 (0.48) | HTR6PTPRCGAAPOLBGFER | |
| SCHEMBL12087024 | 0.81 | GAA (0.69) | HTR6GAAPOLBGFERKMT2A | |
| SCHEMBL2350373 | 0.78 | AKR1B1 (0.51) | HTR6GAAPOLBGFERKMT2A | |
| SCHEMBL16810 | 0.78 | HSD11B1 (0.57) | HTR6GAAPOLBGFERKIF18A | |
| SCHEMBL227808 | 0.77 | KIF18A (0.57) | HTR6GAAPOLBGFERS100A4 | |
| SCHEMBL16495237 | 0.75 | TSHR (0.45) | HTR6GAAPOLBGFERKMT2A | |
| SCHEMBL9793431 | 0.74 | HTR6 (0.62) | HTR6GAAPOLBGFERKMT2A | |
| SCHEMBL16487 | 0.74 | HTR6 (0.70) | HTR6GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL28227769 | 0.74 | HTR6 (0.70) | HTR6GAAPOLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519554-B1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | DU PONT (US) | 2016-03-16 | — | — | EP | disclosed |
| US-8609804-B2 | Polyarylene polymers and processes for preparing | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-12-17 | — | — | US | disclosed |
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120322973-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120302725-A1 | POLYARYLENE IONOMERS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120302725-A1 | POLYARYLENE IONOMERS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-29 | — | — | US | disclosed |
| US-20120296065-A1 | POLYARYLENE IONOMERS MEMBRANES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120296065-A1 | POLYARYLENE IONOMERS MEMBRANES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120289678-A1 | METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120289678-A1 | METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-15 | — | — | US | disclosed |
| EP-2519554-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E.I. Du Pont De Nemours And Company (US) | 2012-11-07 | — | — | EP | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2011090705-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011090705-A2 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011082197-A1 | POLYARYLENE IONOMERIC MEMBRANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082158-A1 | POLYARYLENE IONOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082167-A1 | METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082167-A1 | METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011082197-A1 | POLYARYLENE IONOMERIC MEMBRANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004387-A1 | POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING | PCBP1, PARG, PARN | HTR6 4302/4885PTPRC 2151/4885GAA 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.