Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 4/20 | 0.39 |
| ▸ | GABRD | O14764 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498270 | 0.83 | ALDH1A1 (0.55) | KMT2AGAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16512392 | 0.81 | ADORA1 (0.43) | KMT2AALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16498369 | 0.76 | KMT2A (0.49) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL16512632 | 0.74 | TDP1 (0.36) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL16498279 | 0.74 | CHEK1 (0.44) | GAAMAPTHSD17B10NPC1POLB | |
| SCHEMBL16498355 | 0.72 | CFTR (0.37) | KMT2AGAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16512390 | 0.70 | PTGER1 (0.40) | KMT2AALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL28364880 | 0.68 | JAK2 (0.41) | ALDH1A1CYP2C9CYP2C19MAPTKDM4E | |
| SCHEMBL16512866 | 0.68 | PTGER1 (0.46) | ALDH1A1CYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL16512871 | 0.68 | ELANE (0.38) | GAAALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |