Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498847 | 0.88 | MAPT (0.36) | MAPTTP53SLC5A1NAMPTLMNA | |
| SCHEMBL16498279 | 0.83 | CHEK1 (0.44) | MAPTSLC5A1NPC1RAB9AHTT | |
| SCHEMBL16512790 | 0.80 | SLC5A1 (0.35) | MAPTTP53SLC5A1NAMPTLMNA | |
| SCHEMBL16498519 | 0.77 | SCN9A (0.40) | CFTRMAPTTP53LMNAALDH1A1 | |
| SCHEMBL16498371 | 0.74 | TP53 (0.41) | MAPTTP53LMNAALDH1A1HPGD | |
| SCHEMBL16498268 | 0.72 | KMT2A (0.42) | MAPTTP53LMNAALDH1A1HPGD | |
| SCHEMBL16512871 | 0.71 | ELANE (0.38) | MAPTSLC5A1ALDH1A1HPGDKDM4E | |
| SCHEMBL16512866 | 0.67 | PTGER1 (0.46) | SLC5A1LMNAALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL16512632 | 0.66 | TDP1 (0.36) | MAPTSLC5A1ALDH1A1HPGDKDM4E | |
| SCHEMBL16498609 | 0.65 | NR1I2 (0.43) | CFTRLMNAALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | claimed |