Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16512390 | 0.82 | PTGER1 (0.40) | PTGER1GRM2SLC5A1ELANEALDH1A1 | |
| SCHEMBL16498311 | 0.79 | CYP2C19 (0.50) | PTGER1RPA1L3MBTL1MGAMALDH1A1 | |
| SCHEMBL16498279 | 0.77 | CHEK1 (0.44) | PTGER1GRM2SLC5A1ELANEL3MBTL1 | |
| SCHEMBL16512392 | 0.74 | ADORA1 (0.43) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16499203 | 0.73 | L3MBTL1 (0.46) | RPA1L3MBTL1MGAMALDH1A1PPP1CA | |
| SCHEMBL16498309 | 0.71 | KEAP1 (0.43) | RPA1L3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16512871 | 0.68 | ELANE (0.38) | PTGER1GRM2SLC5A1ELANEALDH1A1 | |
| SCHEMBL16498268 | 0.68 | KMT2A (0.42) | ALDH1A1CYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL16498355 | 0.67 | CFTR (0.37) | SLC5A1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14151556 | 0.67 | ACMSD (0.48) | PTGER1GRM2ELANEATRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |