Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16498371 | 0.87 | TP53 (0.41) | RAB9AMITFPKMNPC1POLB | |
| SCHEMBL16498355 | 0.83 | CFTR (0.37) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL16498847 | 0.83 | MAPT (0.36) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL16512790 | 0.82 | SLC5A1 (0.35) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL16512871 | 0.80 | ELANE (0.38) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL16498236 | 0.79 | CHEK1 (0.53) | CHEK1AURKACSNK1A1CDK8NEK2 | |
| SCHEMBL16512866 | 0.77 | PTGER1 (0.46) | SLC5A1PTGER1GRM2ELANEL3MBTL1 | |
| SCHEMBL16498268 | 0.74 | KMT2A (0.42) | NPC1POLBHSD17B10GAAMAPT | |
| SCHEMBL16512390 | 0.73 | PTGER1 (0.40) | AURKASLC5A1PTGER1GRM2ELANE | |
| SCHEMBL16512632 | 0.73 | TDP1 (0.36) | SLC5A1PTGER1GRM2ELANERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | claimed |
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |