Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16512632 | 0.82 | TDP1 (0.36) | ELANESLC5A1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16498279 | 0.80 | CHEK1 (0.44) | ELANESLC5A1POLBGAAMAPT | |
| SCHEMBL16498629 | 0.72 | ESR2 (0.47) | G6PDSMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL17111868 | 0.72 | GAA (0.46) | G6PDSMN1; SMN2ALDH1A1KDM4EGLA | |
| SCHEMBL16498355 | 0.71 | CFTR (0.37) | SLC5A1SMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL16498847 | 0.70 | MAPT (0.36) | SLC5A1SMN1; SMN2KDM4EMAPTCHEK1 | |
| SCHEMBL16512790 | 0.70 | SLC5A1 (0.35) | SLC5A1NPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL16498371 | 0.68 | TP53 (0.41) | POLBSMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL16512866 | 0.68 | PTGER1 (0.46) | ELANESLC5A1SMN1; SMN2ALDH1A1GRM2 | |
| SCHEMBL16498268 | 0.68 | KMT2A (0.42) | POLBSMN1; SMN2ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153588-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2011-12-15 | — | — | WO | disclosed |