Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | PKN1 | Q16512 | 4/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RHEB | Q15382 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ridinilazole SCHEMBL413723 | 0.88 | ALDH1A1 (0.66) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| Ridinilazole SCHEMBL29379856 | 0.88 | ALDH1A1 (0.66) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| Ridinilazole SCHEMBL17867397 | 0.82 | NPC1 (0.65) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL16498509 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL22906080 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL6263502 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL14834116 | 0.78 | KDM4E (0.54) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL16499476 | 0.77 | ALDH1A1 (0.65) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL16499516 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EPKN1PKN2HPGD | |
| SCHEMBL19994448 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EPKN1PKN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151620-A1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE | SUMMIT CORPORATION PLC (GB) | 2011-12-08 | — | — | WO | claimed |
| WO-2011151620-A1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE | SUMMIT CORPORATION PLC (GB) | 2011-12-08 | — | — | WO | disclosed |