Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813382 | 0.85 | HSD11B1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL16499157 | 0.80 | RARB (0.34) | CYP11B1CYP11B2AR | |
| SCHEMBL12813495 | 0.80 | CYP3A4 (0.39) | CYP11B1CYP11B2KDM1A | |
| SCHEMBL12813325 | 0.79 | CES2 (0.32) | — | |
| SCHEMBL12813503 | 0.79 | SLC6A4 (0.36) | — | |
| SCHEMBL12813191 | 0.78 | KMT2A (0.33) | — | |
| SCHEMBL16499250 | 0.77 | CYP11B1 (0.37) | CYP11B1CYP11B2S1PR3TRPV4AR | |
| SCHEMBL16498935 | 0.77 | PDE2A (0.45) | — | |
| SCHEMBL12813698 | 0.77 | RXRA (0.33) | — | |
| SCHEMBL12813356 | 0.76 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |