Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.47 |
| ▸ | RARG | P13631 | 6/20 | 0.44 |
| ▸ | RARA | P10276 | 5/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813347 | 0.84 | ALDH1A1 (0.47) | RARBRARGRARARXRANPC1 | |
| SCHEMBL12813381 | 0.81 | RARB (0.41) | RARBRARGRARARXRA | |
| SCHEMBL12813449 | 0.81 | RARB (0.41) | RARBRARGRARARXRANPC1 | |
| SCHEMBL12813465 | 0.81 | RARB (0.43) | RARBRARGRARARXRAALDH1A1 | |
| SCHEMBL16499391 | 0.80 | RARB (0.40) | RARBRARGRARARXRAKDM1A | |
| SCHEMBL12813293 | 0.79 | RARB (0.41) | RARBRARGRARARXRANPC1 | |
| SCHEMBL12813472 | 0.78 | SRD5A2 (0.44) | RARBRARGRARARXRA | |
| SCHEMBL12813501 | 0.77 | HTT (0.45) | RARBRARGRARARXRANPC1 | |
| SCHEMBL8034537 | 0.77 | CYP1A2 (0.49) | RARBRARGRARARXRAMAPT | |
| SCHEMBL12813339 | 0.75 | RARB (0.42) | RARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |