Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.39 |
| ▸ | RXRA | P19793 | 6/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813736 | 0.88 | TAS1R3 (0.40) | RARBRARGRXRARARAMEN1 | |
| SCHEMBL12813035 | 0.86 | HTT (0.49) | RARBRXRAMEN1KMT2ATAS1R3 | |
| SCHEMBL12813470 | 0.86 | RARB (0.38) | RARBCES2CES1RARGRXRA | |
| SCHEMBL16499391 | 0.85 | RARB (0.40) | RARBRARGRXRARARA | |
| SCHEMBL12813449 | 0.84 | RARB (0.41) | RARBCES2CES1RARGRXRA | |
| SCHEMBL16499346 | 0.83 | EPHX2 (0.40) | RARBRARGRXRARARA | |
| SCHEMBL12813501 | 0.83 | HTT (0.45) | RARBCES2CES1RARGRXRA | |
| SCHEMBL12813534 | 0.82 | MEN1 (0.41) | RARBRARGRXRARARAMEN1 | |
| SCHEMBL12813417 | 0.82 | CES2 (0.42) | RARBCES2CES1MEN1KMT2A | |
| SCHEMBL12813381 | 0.81 | RARB (0.41) | RARBCES2CES1RARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |