Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.40 |
| ▸ | MAOA | P21397 | 14/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315565 | 0.77 | MAOB (0.55) | MAOBMAOAPRKCIGRM5 | |
| SCHEMBL7476195 | 0.75 | MAOA (0.43) | MAOBMAOAPRKCIMEN1MAPK1 | |
| SCHEMBL1471642 | 0.74 | MAOB (0.55) | MAOBMAOAPRKCIGRM5 | |
| SCHEMBL7501392 | 0.74 | MEN1 (0.39) | MAOBMAOAPRKCIMEN1MAPK1 | |
| SCHEMBL1513290 | 0.73 | MAOA (0.53) | MAOBMAOA | |
| SCHEMBL13482122 | 0.72 | MAOA (0.43) | MAOBMAOAPRKCIMEN1MAPK1 | |
| SCHEMBL25489095 | 0.72 | DRD2 (0.33) | — | |
| SCHEMBL1815313 | 0.71 | GRM5 (0.44) | MAOBMAOAMEN1KMT2ANPSR1 | |
| SCHEMBL29600467 | 0.71 | MAOA (0.38) | MAOBMAOAPRKCIMEN1MAPK1 | |
| SCHEMBL24362492 | 0.71 | MAOA (0.38) | MAOBMAOAPRKCIMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840076-B1 | BICYCLIC COMPOUND | TOA EIYO LTD (JP) | 2017-10-25 | — | — | EP | disclosed |
| US-9290440-B2 | Bicyclic compound | TOA EIYO LTD. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20150119418-A1 | BICYCLIC COMPOUND | TOA EIYO LTD. (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2840076-A1 | BICYCLIC COMPOUND | TOA Eiyo Ltd. (JP) | 2015-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119418-A1 | BICYCLIC COMPOUND | C1S, C1R, CYP11B2 | MAOB 1357/4885MAOA 1829/4885PRKCI 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.