SCHEMBL1650108

SCHEMBL1650108

CCOC(=O)C(c1c(O)oc2ccccc2c1=O)c1c(O)oc2ccccc2c1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.68
KDM4E B2RXH2 4/20 0.51
HPGD P15428 3/20 0.51
ALDH1A1 P00352 3/20 0.50
NQO1 P15559 2/20 0.50
LMNA P02545 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAOB P27338 1/20 0.48
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
AHR P35869 1/20 0.46
CYP2C9 P11712 5/20 0.45
VKORC1 Q9BQB6 1/20 0.45
PLK1 P53350 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Biscoumacetate SCHEMBL29359768 0.81 ADORA3 (1.00) ADORA3KDM4EALDH1A1NQO1HSD17B10
Ethyl Biscoumacetate SCHEMBL42830 0.81 ADORA3 (1.00) ADORA3KDM4EALDH1A1NQO1HSD17B10
SCHEMBL1649800 0.76 MAOA (0.52) KDM4EHPGDALDH1A1NQO1LMNA
SCHEMBL1649847 0.75 CYP2C9 (0.50) KDM4EHPGDALDH1A1NQO1LMNA
SCHEMBL1651720 0.75 CYP2C9 (0.68) KDM4EALDH1A1NQO1HSD17B10CYP2C9
SCHEMBL414250 0.75 CYP2C9 (0.68) KDM4EALDH1A1NQO1HSD17B10CYP2C9
SCHEMBL5107024 0.74 ADORA3 (0.86) ADORA3KDM4EALDH1A1NQO1HSD17B10
Xanthone SCHEMBL27860392 0.74 RAB9A (0.59) ADORA3KDM4EHPGDALDH1A1LMNA
Xanthone SCHEMBL27310536 0.73 RAB9A (0.61) ADORA3KDM4EHPGDALDH1A1LMNA
SCHEMBL20806 0.72 CYP2C9 (0.73) KDM4EHPGDALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed