Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13261276 | 0.88 | ALDH1A1 (0.50) | MAPTALDH1A1ESR2GPR119HSD17B10 | |
| SCHEMBL16501442 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1ESR2GPR119SMN1; SMN2 | |
| SCHEMBL16501433 | 0.83 | SCD (0.50) | MAPTALDH1A1ESR2CKS1BSKP1 | |
| SCHEMBL16501427 | 0.79 | RAB9A (0.46) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16501435 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1ESR2GPR119SMN1; SMN2 | |
| SCHEMBL16652717 | 0.77 | GPR119 (0.59) | MAPTALDH1A1GPR119SMN1; SMN2LMNA | |
| SCHEMBL13261275 | 0.76 | GPR119 (0.53) | MAPTGPR119CKS1BSKP1SKP2 | |
| SCHEMBL16501444 | 0.76 | SLC6A7 (0.48) | — | |
| SCHEMBL3605523 | 0.75 | GPR119 (0.59) | MAPTALDH1A1GPR119LMNACKS1B | |
| SCHEMBL24964179 | 0.74 | GPR119 (0.61) | MAPTALDH1A1GPR119SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301143-A1 | HETEROCYCLIC DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK CANADA INC. (CA) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301143-A1 | HETEROCYCLIC DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, COASY | MAPT 3518/4885ALDH1A1 1696/4885ESR2 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.