Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278353 | 0.82 | CYP3A4 (0.52) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL7180551 | 0.82 | CYP3A4 (0.52) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL8694424 | 0.81 | CA1 (0.66) | CYP3A4TDP1ALDH1A1HSD17B10CA2 | |
| SCHEMBL3044709 | 0.78 | CYP3A4 (0.48) | CYP3A4TSHRTDP1MAPK1CA2 | |
| SCHEMBL242025 | 0.78 | CA2 (0.68) | CYP3A4TSHRTDP1CA2CA1 | |
| SCHEMBL31148855 | 0.78 | CYP3A4 (0.48) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL2278953 | 0.78 | POLB (0.53) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL10348147 | 0.78 | CYP3A4 (0.48) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL13651653 | 0.78 | TDP1 (0.41) | CYP3A4TSHRTDP1MAPK1ALDH1A1 | |
| SCHEMBL15430 | 0.78 | CYP3A4 (0.70) | CYP3A4TSHRTDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365056-B2 | Substituted 9a-N-(N′-(sulfonyl)phenylcarbamoyl)derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithomycin A and 5-0-desosaminyl-9-deoxo-9-dihydro-9-a-aza-9a-homoerithronolide A | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O (HR) | 2008-04-29 | — | — | US | claimed |
| EP-1575969-B1 | SUBSTITUTED 9a-N-(N'- 4-(SULFONYL)PHENYL CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL-9-DEOXO-9-DI-HYDRO-9A-AZA-9A-HOMOERITHRONOLIDE A | PLIVA ISTRAZIVACKI INST D D O (HR) | 2006-07-12 | — | — | EP | claimed |
| US-20060084795-A1 | Substituted 9a-n-[n'-(benzenesulfonyl)carbamoyl-aminopropyl]and 9a-n-[n'-(b-cya-neothyl) -n-[n'-(benzenesulfonyl)carbamoyl-y-aminopropyl]derivatives of 9-deoxo-9-dihydro-9a-aza- 9a-homoerithromycin a and 5-0-aza-homoerithronolide a | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2006-04-20 | — | — | US | claimed |
| EP-1575969-A1 | SUBSTITUTED 9a-N-(N'- 4-(SULFONYL)PHENYL CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL-9-DEOXO-9-DI-HYDRO-9A-AZA-9A-HOMOERITHRONOLIDE A | Pliva-Istrazivacki Institut D.D.O. (HR) | 2005-09-21 | — | — | EP | claimed |
| WO-2004043985-A1 | SUBSTITUTED 9A-N-{N'-[4-(SULFONYL)PHENYL]CARBAMOYL} DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9A-AZA-9A-HOMOERITHROMYCIN A AND 5-0-DESOSAMINYL-9-DEOXO-9-DI-HYDRO-9A-AZA-9A-HOMOERITHRONOLIDE A | PLIVA - ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2004-05-27 | — | — | WO | claimed |
| EP-0154811-A2 | Coupling agents between mineral fillers and polymers | Plüss-Staufer AG (CH) | 1985-09-18 | — | — | EP | claimed |
| WO-1985003505-A2 | COUPLING AGENT BETWEEN MINERAL FILLERS AND POLYMERS | PLÜSS-STAUFER AG (CH) | 1985-08-15 | — | — | WO | claimed |
| CN-121260915-A | Electrolyte and lithium ion battery | 江苏国轩新能源科技有限公司 | 2026-01-02 | — | — | CN | disclosed |
| EP-3774961-B1 | ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS | COVESTRO DEUTSCHLAND AG (DE) | 2025-01-15 | — | — | EP | disclosed |
| EP-4464727-A1 | ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2024-11-20 | — | — | EP | disclosed |
| US-20240300968-A1 | 6-SUBSTITUTED NAPHTHALENE-1,3-DISULFONIC ACID DERIVATIVES AS MODULATORS OF THE EXTRACELLULAR NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE (ENAMPT) FOR THE TREATMENT OF E.G. DIABETES | UNIV MANCHESTER (GB) | 2024-09-12 | — | — | US | disclosed |
| EP-4377300-A1 | 6-SUBSTITUTED NAPHTHALENE-1,3-DISULFONIC ACID DERIVATIVES AS MODULATORS OF THE EXTRACELLULAR NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE (ENAMPT) FOR THE TREATMENT OF E.G. DIABETES | The University of Manchester (GB) | 2024-06-05 | — | — | EP | disclosed |
| US-20240150515-A1 | Low Viscosity Catalyst Compositions for Producing Isocyanurate Polymers | COVESTRO DEUTSCHLAND AG (DE) | 2024-05-09 | — | — | US | disclosed |
| US-4342869-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | disclosed |
| US-4338437-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338438-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | disclosed |
| US-4324890-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1982-04-13 | — | — | US | disclosed |
| US-4297488-A | 7-α-Methoxy cephalosporins | MERCK & CO., INC. (US) | 1981-10-27 | — | — | US | disclosed |
| US-4086209-A | Novel nitrogen-containing aromatic polymers and process for their preparation | TEIJIN LIMITED (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4031068-A | Non-migratory sulfonyl azide antioxidants | UNIROYAL INC. (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300968-A1 | 6-SUBSTITUTED NAPHTHALENE-1,3-DISULFONIC ACID DERIVATIVES AS MODULATORS OF THE EXTRACELLULAR NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE (ENAMPT) FOR THE TREATMENT OF E.G. DIABETES | NAPRT, NAMPT, NUDT1 | CYP3A4 3331/4885TSHR 3228/4885TDP1 2294/4885 |
| US-20060084795-A1 | Substituted 9a-n-[n'-(benzenesulfonyl)carbamoyl-aminopropyl]and 9a-n-[n'-(b-cya-neothyl) -n-[n'-(benzenesulfonyl)carbamoyl-y-aminopropyl]derivatives of 9-deoxo-9-dihydro-9a-aza- 9a-homoerithromycin a and 5-0-aza-homoerithronolide a | HEXA, HINT1, CDA | CYP3A4 806/4885TSHR 3140/4885TDP1 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.